Lauren Scott joined the Meredith College athletics staff in spring of 2012 as the first head women's lacrosse coach. Under Scotts leadership the Avenging Angels program has earned six consecutive conference tournament championships, four conference Rookie of the Year awards, five Player of the Year honors, as well as four Coach of the Year selections. The 2016 team secured a place in NCAA Division III history as the National Scoring Offense Statistical Champion, and the 2019 squad followed as the national leader with a 0.566 shot percentage.

Scott's 2019 graduates departed Meredith with an undefeated USA South career record, four conference tournament and regular season championships, four NCAA appearances, and four USA South Women's Lacrosse Sportsmanship Awards. Holly Hite collected her second All-American honor after being named the USA South Player of the Year, alongside Coach of the Year Scott.

MC Lax captured the program's first-ever NCAA tournament win in May 2018 defeating the United States Merchant Marine Academy to advance to a second round pairing with Salisbury University. The Avenging Angels earned the USA South Regular Season title and defended the Tournament Championship to earn the automatic qualifier. Three-time conference POY Carlee Joseph earned the coveted USA South Don Scalf Female Athlete of the Year honor and went on to be named the Division III Scholar-Athlete of the Year recipient. Holly Hite was named a third team All-American and both players garnered All-Region first team honors. Cameron Ruffin joined Joseph as a member of the Division III Senior All-Start team.

The 2017 Avenging Angels captured the USA South Regular Season and Tournament Championship titles, advancing to the NCAA tournament for the fourth consecutive season. Carlee Joseph earned her second Conference Player of the Year honor and was named All-Chesapeake Region alongside Holly Hite. She also earned the program's first CoSida Academic All-District selection and joined Jennifer Halvorson and Cameron Ruffin on the IWLCA Division III Honor Roll. The team collected the program's third IWLCA Honor Squad recognition as well.

In 2016 Meredith lacrosse secured the USA South Regular Season crown for the first time with an undefeated league record and earned a number one ranking in the NCAA Division III Mid-South Region. The Angels only regular season loss came at the hands of nationally ranked Mary Washington.